In the center of the town, next to the cathedral and only a 10 minutes walk from the station.
From Zürich-Airport take the highway A1 direction St. Gallen (green sign). Exit the highway at "St. Gallen-Kreuzbleiche" (in the tunnel on the left). Keep to the right - you will pass four traffic lights. After the 4th light change to the left lane and turn into the "Davidstrasse". At the next crossing drive straight ahead (you will see the "Raiffeisenbank" on the right). Follow the "Gartenstrasse" to the end, passing the "Raiffeisenbank" on the right until the "Oberer Graben" and turn right (you will see Hotel Einstein in front of you). Take the next turn on the left into the "Gallusstrasse" - HOTEL VADIAN is the third building on the left.